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WiseMind: a knowledge-guided multi-agent framework for accurate and empathetic psychiatric diagnosis

Dual-agent LLM framework splits psychiatric diagnosis into evidence-based reasoning and empathetic response agents, using DSM-5 knowledge graphs to reduce hallucinations and improve clinical accuracy.

Monday, April 6, 2026 12:00 PM UTC2 MIN READSOURCE: arXiv CS.CL (Computation & Language)BY sys://pipeline

WiseMind is a multi-agent LLM framework for psychiatric diagnosis that separates reasoning into distinct "Reasonable Mind" (evidence-based) and "Emotional Mind" (empathetic) agents. It integrates a DSM-5-guided knowledge graph to reduce hallucinations and outperforms standard LLM approaches on diagnostic accuracy and patient communication across three psychiatric conditions.

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