How OpenEvidence built a healthcare AI that physicians actually trust

OpenEvidence, the most widely used clinical decision support platform among U.S. clinicians, supports over 20 million clinical consultations monthly and treats over 100 million Americans annually. The platform achieves hospital-grade reliability while moving at startup speed through a hybrid architecture: Python backend on Google Cloud Platform and Next.js frontend on Vercel. When OpenEvidence unexpectedly went viral on TikTok (2M views in a week), the infrastructure handled the surge seamlessly without additional provisioning, and Vercel's Fluid compute reduced serverless costs by 90%.